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NANOG Protein

Homeobox protein NANOG, Homeobox transcription factor Nanog, hNanog

Catalog No. Product Name Size List Price (US$) Quantity
BP002381-PRO-896 Recombinant Human Homeobox protein NANOG 20 ug 160.00
BP002381-PRO-896 Recombinant Human Homeobox protein NANOG 1 mg 2700.00
Description

Introduction
NANOG is a multidomain homeobox transcription factor which functions to maintain the undifferentiated state of pluripotent stem cells. NANOG expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53.

BP002381-PRO-896: Recombinant Human Homeobox protein NANOG (NANOG)

Source: E. coli-derived.
Recombinant Human NANOG protein is a single, non-glycosylated polypeptide chain containing 305 amino acids (1-305) and having a molecular mass of 34.6 kDa. The NANOG protein is purified by proprietary chromatographic techniques.
Purity: > 90% as determined by SDS-PAGE.
Formulation: The NANOG solution (1 mg/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 0.4 M Urea and 5% glycerol.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other NANOG Proteins:
Recombinant Human Homeobox protein NANOG, His Tag
Recombinant Human Homeobox protein NANOG-TAT

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