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MIP-1A Antibody

MIP-1-alpha/CCL3 Antibody

Catalog No. Product Name Size List Price (US$) Quantity
PA004045-ANT-118 MIP 1a Monoclonal Antibody 500 ug 160.00
PA004045-ANT-118 MIP 1a Monoclonal Antibody 1 mg 290.00
Description

Introduction
Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). It is found at the site of tooth eruption and bone degradation. In the bone, CCL2 is expressed by mature osteoclasts and osteoblasts and is under the control of nuclear factor ?B (NF-?B). CCL2 recruits immune cells, such as monocytes, to sites of tissue injury and infection. This chemokine is produced as a protein precursor containing signal peptide of 23 amino acids and a mature peptide of 76 amino acids. It is a monomeric polypeptide, with a molecular weight of approximately 13kDa. As with many other CC chemokines, CCL2 is located on chromosome 17 in humans. The cell surface receptors that bind CCL2 are CCR2 and CCR5.

PA004045-ANT-118: MIP 1a Monoclonal Antibody

Mouse Monoclonal Antibody.
Applications: By direct ELISA, 1:20,000 dilution will yield >1.0 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories) UsageProspec's products are furnished for LABORATORY ESEARCH USE ONLY.
Reactivity: Human.
Immunogen: r.Human MIP1-a.
Purification: Ion exchange.
Form of Antibody: 1ug/ml in PBS (after reconstitution).
Clone: YNR-HMIP1a.
Isotype: Mouse IgG1.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

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