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MDH1 Enzyme

Malate dehydrogenase cytoplasmic, Cytosolic Malate Dehydrogenase, Diiodophenylpyruvate Reductase, MDHA

Catalog No. Product Name Size List Price (US$) Quantity
BP000579-ENZ-273 Recombinant Chicken MDH1 Enzyme 5000 IU 160.00
BP000579-ENZ-273 Recombinant Chicken MDH1 Enzyme 50000 IU 990.00
Description

Introduction
Malate Dehydrogenase, Cytoplasmic (MDH1) is an enzyme which belongs to the MDH Type 2 sub-family of LDH/MDH superfamily. MDH1 is involved in the Citric Acid Cycle that catalyzes the conversion of Malate into Oxaloacetate (using NAD+) and vice versa. MDH1 should not be confused with Malic Enzyme, which catalyzes the conversion of Malate to Pyruvate, producing NADPH. MDH1 also participates in Gluconeogenesis, the synthesis of Glucose from smaller molecules. Pyruvate in the mitochondria is acted upon by Pyruvate Carboxylase to form Pxaloacetate, a Citric Acid Cycle intermediate. In order to transport the Oxaloacetate out of the Mitochondria, Malate Dehydrogenase reduces it to Malate, and it then traverses the inner Mitochondrial membrane. Once in the cytosol, the Malate is oxidized back to Oxaloacetate by MDH1. Finally, Phosphoenol-Pyruvate Carboxy Kinase (PEPCK) converts Oxaloacetate to Phosphoenol Pyruvate.

BP000579-ENZ-273: Recombinant Chicken Malate Dehydrogenase Cytoplasmic (MDH1) Enzyme

Source: E. coli-derived.
Specific Activity Greater than 710 U/mg protein.
Purity: > 95% by RP-HPLC and SDS-PAGE.
Formulation: Each mg of protein contains 0.59 mg NaPO4.
Reconstitution: It is recommended to reconstitute the lyophilized Malate dehydrogenase in sterile 18 MΩ-cm H2O.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other MDH1 Enzymes:
Recombinant MDH1 Enzyme
Recombinant Human MDH1 Enzyme
Recombinant Human MDH1 Enzyme

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