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Conditions of optimal LSM1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
U6 snRNA-Associated Sm-Like Protein LSm1 (LSM1) belongs to the snRNP Sm proteins family. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which plays an important role in pre-mRNA splicing. LSM1 binds specifically to the 3-terminal U-tract of U6 snRNA. LSM1 can interact with SLBP when histone mRNA is being rapidly degraded during the S phase. In addition, LSM1 is associated with cellular transformation and the progression of several malignancies including mesothelioma, lung cancer and breast cancer.
BP001616-PRO-259: Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm1 (LSM1) Protein
Source: E. coli-derived.
Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm1 (LSM1) Protein fused with a 20 amino acid His tag at N-terminus is a single, non-glycosylated, polypeptide chain containing 153 amino acids (1-133 a.a.) and having a molecular mass of 17.3 kDa. The LSM1 is purified by proprietary chromatographic techniques.
Purity: > 95% by SDS-PAGE.
Formulation: The LSM1 solution (1 ug/ml) contains 20 mM Tris-HCl buffer (pH 7.5), 1 mM DTT, 10% glycerol and 0.1 M NaCl.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other LSM1 Proteins:
Recombinant Human LSM1 Protein
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