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LSM1 Protein

U6 snRNA-Associated Sm-Like Protein LSm1, Cancer-Associated Sm-Like, Small Nuclear Ribonuclear CaSm, CASM

Catalog No. Product Name Size List Price (US$) Quantity
BP001616-C262 Recombinant Human LSM1 Protein 10 ug 180.00
BP001616-C262 Recombinant Human LSM1 Protein 50 ug 528.00
BP001616-C262 Recombinant Human LSM1 Protein 1 mg 2640.00
Description

Introduction
U6 snRNA-Associated Sm-Like Protein LSm1 (LSM1) belongs to the snRNP Sm proteins family. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which plays an important role in pre-mRNA splicing. LSM1 binds specifically to the 3-terminal U-tract of U6 snRNA. LSM1 can interact with SLBP when histone mRNA is being rapidly degraded during the S phase. In addition, LSM1 is associated with cellular transformation and the progression of several malignancies including mesothelioma, lung cancer and breast cancer.

BP001616-C262: Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm1 (LSM1) Protein

Source: E. coli-derived.
Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm1 (LSM1) Protein is expressed with sequence (Met1-Tyr133) of Human LSM1 fused with a His tag at the C-terminus.
Purity: > 95% by reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other LSM1 Proteins:
Recombinant Human LSM1 Protein

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