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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal LMNA Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
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Introduction
Lamin-A is a major component of the nuclear lamina, a dynamic meshwork located just under the nuclear envelope and it is encoded by lamin A/C gene (LMNA). Lamin-A is synthesized as Prelamin A, a longer precursor that in vivo goes through a serial post-translational modifications that lead to mature Lamin A. Diverse mutations in the Lamin A/C gene are associated with different diseases that are collectively called laminophaties, including Emery-Dreifuss muscular dystrophy, familiar partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.
BP002686-PRO-690: Recombinant Human Lamin-A/C (LMNA) protein
Source: E. Coli-derived.
Recombinant Human Lamin A produced in E. Coli is a single, non-glycosylated polypeptide chain containing 645 amino acids and having a molecular mass of 70 kDa.
Purity: > 90% by SDS-PAGE.
Formulation: The Lamin-A Protein solution (0.9 mg/ml) contains 20 mM phosphate buffer pH 7.0, 500 mM NaCl, 1 mM DTT, 1.5 mM EDTA and 20% (v/v) Glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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