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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal LLC Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Lambda light chain is the smaller of the two types of polypeptide chains in immunoglobulins, consisting of an antigen-binding segment with a variable amino acid sequence, and a constant region with a relatively unchanging amino acid sequence. The lambda light chain gene is located on chromosome 22. The immunoglobulin heavy chains (G, A, M, D, or E) and light chains (kappa or lambda) are produced separately by the plasma cells in the bone marrow. The kappa and lambda molecules are attached to the heavy chains and whole immunoglobulins are assembled, and then conveyed to the surface of the plasma cell. Small amounts of free kappa and lambda light chains are found in the serum of healthy individuals since they are produced in excess. An accurate measurement of serum levels of free light chains in the presence of a great excess of bound light chains has been quite tricky for many years due to their identical structure. A number of diseases affect the production of free light chains by the plasma cells in the bone marrow, causing abnormal levels in the serum, urine or cerebrospinal fluid.
Lambda along with kappa light chains can be used as a tumor marker in urine.
BP000498-PRO-561: Human Lambda Light Chain (LLC) Protein
Source: Pooled Bence Jones urine-derived.
Predicted molecular mass: 23 kDa.
Purity: > 96%.
Formulation: Lyophilized from 0.02 M NH4HCO3.
Reconstitution: It is recommended to reconstitute the lyophilized Human Lambda light chain in sodium acetate buffer at pH 4.0 containing 0.5 M NaCl.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
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