Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
|---|
Conditions of optimal JAM-A Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Junctional adhesion molecule A, also known as Junctional adhesion molecule 1, Platelet F11 receptor, Platelet adhesion molecule 1, JAM1, JCAM, F11R, is a single-pass type I membrane protein that Belongs to the immunoglobulin superfamily. F11R contains 2 Ig-like V-type (immunoglobulin-like) domains and Interacts with the ninth PDZ domain. F11R localized at tight junctions of both epithelial and endothelial cells. F11R seems to involve in epithelial tight junction formation. F11R appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. F11R plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. In case of orthoreovirus infection, F11R serves as receptor for the virus.
BP001370-PRO-1112: Recombinant Human Junctional adhesion molecule A (JAM-A) Protein
Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 238 amino acids (26-238 a.a) and having a molecular mass of 25.8 kDa. F11R is fused to a 25 amino acid His-tag at N-terminus.
Purity: > 90% by SDS-PAGE.
Formulation: F11R protein solution (1 ug/ml) containing 20 mM Tris-HCl buffer (pH8.0), 10% glycerol, 0.15 M NaCl and 1 mM DTT.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other JAM-A Protein:
Recombinant Human JAM-A Protein
Copyright © 2009-2022 sydlabs.com. All rights reserved.
Use of this website means that you have read, understood, and accepted the Syd Labs Privacy Policy and Terms & Conditions.