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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal IL 23 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
IL23 is composed of a subunit of the heterodimeric cytokine IL23 and the p40 subunit of interleukin 12 (IL12B). Interleukin-23 (IL-23) belongs to the IL-12 family and is produced by antigen presenting cells. IL-23 using IL12RB1 and IL-23R (specific for IL-23) can activate STAT and NF-kB pathways and stimulate the production of interferon-gamma. ). IL-23 is known to take a vital part in the inflammation process and is associated with auto immune diseases. However, unlike IL12, which acts primarily on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells.
BP002449-CYT-050: Recombinant Human Interleukin-23 (IL 23) Protein
Source: HEK-derived.
A glycosylated disulfide linked homodimer, having a total molecular weight of 43 kDa and 19 kDa heterodimer.
The activity, as determined by the dose dependent secretion of h-IFN-g from human PBMC was found to be 2 to 20 ng/ml ED50.
Purity: > 95.0% as determined by analysis by SDS-PAGE.
Formulation: IL-23 was lyophilized from a concentrated (480 ug/ml) sterile solution containing 1x PBS.
Reconstitution: It is recommended to reconstitute the lyophilized Interleukin-23 in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other IL 23 Proteins:
Recombinant Human Interleukin-23, His Tag Protein
IL-23 Antibodies:
IL-23 Polyclonal Antibody
IL-23 ELISA Kits:
Mouse IL-23 ELISA Kit
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