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IL-2 Protein

Interleukin-2, T-Cell Growth Factor, TCGF, Aldesleukin, IL2

Catalog No. Product Name Size List Price (US$) Quantity
BP000145-CYT-209 Recombinant Human IL-2 Protein 50 ug 160.00
BP000145-CYT-209 Recombinant Human IL-2 Protein 1 mg 720.00
Description

Introduction
IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

BP000145-CYT-209: Recombinant Human Interleukin-2 (IL-2) Protein

Source: E. coli-derived.
A single, non-glycosylated mutein (variant form) of human IL-2 polypeptide chain containing 134 amino acids and having a molecular mass of 15517 Dalton.
N-terminal sequence analysis: Met-Ala-Pro-Thr-Ser.
The ED50 as determined by the dose-dependant stimulation of murine CTLL-2 cells is < 0.0645 ug/ml, corresponding to a Specific Activity of 15.5 MIU/mg.
Purity: > 98% by SDS-PAGE and RP-HPLC.
Formulation: Lyophilized after extensive dialysis against 0.17 mg sodium monobasic & 0.89 mg dibasic sodium phosphate buffer to a pH=7.5.
Reconstitution: It is recommended to reconstitute the lyophilized Interleukin 2 in sterile 20 mM AcOH not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other IL-2 Proteins:
Recombinant Porcine IL-2 Protein
Recombinant Mouse IL-2 Protein, His Tag
Recombinant Mouse IL-2 Protein
Recombinant Human IL-2 Protein, His Tag
Recombinant Human IL-2 Protein, HEK
Recombinant Human IL-2 Protein
Recombinant Human IL-2 Protein
Recombinant Rat IL-2 Protein

IL-2 Antibodies:
IL-2 Polyclonal Antibody
IL-2 Polyclonal Antibody
IL-2 Monoclonal Antibody
IL-2 Monoclonal Antibody
IL-2 Monoclonal Antibody

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