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IL-1RA Protein

Interleukin-1 Receptor Antagonist Protein, IL-1RN, IL-1ra, IRAP, ICIL-1RA, IL1 Inhibitor, Anakinra, IL1RN, IL1F3, IL1RA

Catalog No. Product Name Size List Price (US$) Quantity
BP000144-CYT-658 Recombinant Mouse IL-1RA Protein 20 ug 160.00
BP000144-CYT-658 Recombinant Mouse IL-1RA Protein 1 mg 3000.00
Description

Introduction
Interleukin-1 ra is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

BP000144-CYT-658: Recombinant Mouse Interleukin-1 Receptor Antagonist Protein (IL-1RA) Protein

Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 153 amino acids and having a molecular mass of 17.4 kDa.
N-terminal sequence analysis: Ala-Cys-Arg-Pro-Ser-Gly.
The mouse IL-1Ra is capable of inhibiting IL-1-alpha activity in helper T cell line D10.G4.1.
Purity: > 98% by SDS-PAGE and RP-HPLC.
Formulation: Lyophilized from a concentrated (1 ug/ml) solution in water containing NaHCO3.
Reconstitution: It is recommended to reconstitute the lyophilized Interleukin-1ra in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other IL-1RA Proteins:
Recombinant Rat IL-1RA Protein
Recombinant Mouse IL-1RA Protein, His Tag
Recombinant Human IL-1RA Protein, His Tag
Recombinant Human IL-1RACP Protein
Recombinant Human IL-1RA Protein
Recombinant Human IL-1RA Protein

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