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Conditions of optimal IL-1RA Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Interleukin-1 ra is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
BP000144-CYT-658: Recombinant Mouse Interleukin-1 Receptor Antagonist Protein (IL-1RA) Protein
Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 153 amino acids and having a molecular mass of 17.4 kDa.
N-terminal sequence analysis: Ala-Cys-Arg-Pro-Ser-Gly.
The mouse IL-1Ra is capable of inhibiting IL-1-alpha activity in helper T cell line D10.G4.1.
Purity: > 98% by SDS-PAGE and RP-HPLC.
Formulation: Lyophilized from a concentrated (1 ug/ml) solution in water containing NaHCO3.
Reconstitution: It is recommended to reconstitute the lyophilized Interleukin-1ra in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other IL-1RA Proteins:
Recombinant Rat IL-1RA Protein
Recombinant Mouse IL-1RA Protein, His Tag
Recombinant Human IL-1RA Protein, His Tag
Recombinant Human IL-1RACP Protein
Recombinant Human IL-1RA Protein
Recombinant Human IL-1RA Protein
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