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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal IL-10 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
IL10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway.
BP000133-CYT-497: Recombinant Mouse Interleukin-10 (IL-10) Protein
Source: E. coli-derived.
Predicted molecular mass: 18785 Dalton.
N-terminal sequence analysis: Met-Ser-Arg-Gly-Gln.
The ED50 as determined by the dose-dependant co-stimulation with IL-4 of mouse MC-9 cells was found to be < 2 ug/ml, corresponding to a Specific Activity of 500,000 IU/mg.
Purity: > 98% by SDS-PAGE and RP-HPLC.
Formulation: Lyophilized after extensive dialysis against PBS.
Reconstitution: It is recommended to reconstitute the lyophilized IL-10 Mouse Recombinant in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other IL-10 Proteins:
Recombinant Rat IL-10 Protein
Recombinant Rat IL-10 Protein
Recombinant Mouse IL-10 Protein
Recombinant Porcine IL-10 Protein
Recombinant Human IL-10 Protein, His
Recombinant Human IL-10 Protein, HEK
Recombinant Human IL-10 Protein
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