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Conditions of optimal HDAC8 Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Histone deacetylase 8 (HDAC8) is a member of the class 1 of the histone deacetylase/acuc/apha family. HDAC8 is biologically involved in skull morphogenesis and metabolic control of the ERR-alpha/PGC1-alpha transcriptional complex. Histones play a key role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation modifies chromosome structure and affects transcription factor access to DNA.
BP002588-ENZ-210: Recombinant Human Histone Deacetylase 8 (HDAC8) Enzyme
Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 383 amino acids (1-377) and having a molecular mass of 42.6 kDa. HDAC8 is fused to a 6 amino acid His-tag at C-terminus.
Purity: > 80% as determined by SDS-PAGE.
Formulation: The HDAC8 solution (0.25 mg/ml) contains 20 mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1 M NaCl and 1 mM DTT.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
HDAC8 Antibodies:
HDAC8 Polyclonal Antibody
HDAC8 Polyclonal Antibody
HDAC8 (Phospho-Ser39) Polyclonal Antibody
HDAC8 (Ab-39) Polyclonal Antibody
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