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Conditions of optimal HDAC8 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Description
Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups from an E-N-acetyl lysine amino acid on a histone or other proteins. Its action is opposite to that of histone acetyltransferase. HDAC proteins are found in three groups, the first two groups belong to the classical HDACs and their activities are inhibited by trichostatin A (TSA) whereas the third group is a family of NAD+-dependent proteins not affected by TSA. Homologues to all three groups are found in yeast having the names reduced potassium dependency 3 (Rpd3) - corresponds to class 1, histone deacetylase 1 (hda1) to class 2 and silent information regulator 2(Sir2) class3 Affinity purified rabbit polyclonal anti-HDAC 8 antibody is developed with c-terminal peptide of human histone deacetylase 8. It could be used for detection and isolation of HDAC 8.
PA000380-PA1591: HDAC8 Polyclonal Antibody
Rabbit Polyclonal Antibody.
Applications: WB 0.1-0.5 ug/ml; IHC-P 0.5-1 ug/ml.
Reactivity: Human, Rat, Mouse.
Immunogen: A synthetic peptide mapping at the N-terminal of human HDAC8, different from the related mouse and rat sequences by two amino acids.
Purification: Immunogen affinity purified.
Form of Antibody: Lyophilized.
Reconstitution: 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Isotype: Rabbit IgG.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Other HDAC8 Antibodies:
HDAC8 Polyclonal Antibody
HDAC8 (Ab-39) Polyclonal Antibody
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