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HBV Protein

Hepatitis B virus

Catalog No. Product Name Size List Price (US$) Quantity
BP000416-HBV-269 Recombinant HBV Core (1-183 a.a.) 100 ug 160.00
BP000416-HBV-269 Recombinant HBV Core (1-183 a.a.) 500 ug 600.00
BP000416-HBV-269 Recombinant HBV Core (1-183 a.a.) 1000 ug 1200.00
Description

Introduction
Hepatitis B is one of a few known non-retroviralviruses which employ reverse transcriptionas a part of its replication process. (HIV, a completely unrelated virus, also uses reverse transcription, but it is a retrovirus.) HBV invades the cell by binding to surface receptor and become internalized. The viral core particles then migrate to the hepatocyte nucleus and the partially double-stranded, relaxed circular genomes (RC-DNA) are repaired to form a covalently closed circular DNA (cccDNA), which is the template for viral genomic and sub-genomic RNAs by cellular RNA polymerase II. Of these, the pregenomic RNA (pgRNA is selectively packaged into progeny capsids and is then reverse-transcribed into new RC-DNA. The core can either bud into the endoplasmic reticulum to be enveloped or exported from the cell or recycled back into the genome for conversion to cccDNA.

BP000416-HBV-269: Recombinant HBV Core (1-183 a.a.)

Source: E. coli-derived.
Predicted molecular mass: 18 kDa.
Purity > 95%, by SDS-PAGE.
Formulation: 7.5 mM phosphate buffer pH-7.2, 75 mM NaCl and 50% glycerol.
Applications: WB, ELISA.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other HBV Proteins:
Recombinant HBV Protein X
Recombinant HBV HBe
Recombinant HBV Core delta
Recombinant HBV HBe

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