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Conditions of optimal FosB antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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BACKGROUND
FOSB, FBJ murine osteosarcoma viral oncogene homolog B, is a protein that, in humans, is encoded by the FOSB gene. FOSB is a member of Fos gene family which consists of 4 members: FOS, FOSB,FOSL1, and FOSL2. The FOS proteins have been implicated as regulators of cell proliferation,differentiation, and transformation. The FOSB gene is mapped to 19q13.32. Delta FOSB is a truncated splice variant of FOSB. Delta FosB has been implicated in the development of drug addiction and control of the reward system in the brain, and is linked to changes in a number of other gene products such as CREB and sirtuins. Delta FosB also regulates the commitment of mesenchymal precursor cells to the adipocyte or osteoblast lineage.
PA001665-B0930: FosB (Ab-27) Polyclonal Antibody
Rabbit Polyclonal Antibody.
Specificity/Sensitivity: FosB (Ab-27) antibody detects endogenous levels of total FosB protein.
Applications: WB: 1:500~1:1000 IF: 1:500~1:1000 ELISA: 1:5000.
Reactivity: Human, Mouse.
Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human FosB around the phosphorylation site of serine 27 (Y-L-SP-S-V).
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form of Antibody: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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