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FGF2 Protein

Fibroblast Growth Factor 2, FGF-2, Basic Fibroblast Growth Factor, bFGF, Heparin-Binding Growth Factor 2, HBGF-2, Fgf-2

Catalog No. Product Name Size List Price (US$) Quantity
BP000183-CYT-218 Recombinant Human FGF2 Protein 50 ug 160.00
BP000183-CYT-218 Recombinant Human FGF2 Protein 1 mg 1080.00
Description

Introduction
FGF-basic is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from AUG and non-AUG (CUG) initiation codons resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

BP000183-CYT-218: Recombinant Human Fibroblast Growth Factor 2 (FGF2) Protein

Source: E. coli-derived.
A single, non-glycosylated, polypeptide chain containing 155 amino acids and having a molecular mass of 17353 Dalton.
The ED50, calculated by the dose-dependant proliferation of BAF3 cells expressing FGF receptors (measured by 3H-thymidine uptake) is <0.5 ng/ml, corresponding to a specific activity of 2,000,000 Units/mg.
Purity: > 96% by SDS-PAGE and RP-HPLC.
Formulation: The protein was lyophilized from a concentrated (1 ug/ml) solution in PBS, pH 7.4.
Reconstitution: It is recommended to reconstitute the lyophilized Fibroblast Growth Factor Basic in sterile 18 MΩ-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Shipping: The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other FGF2 Proteins:
Recombinant Rat FGF2 Protein
Recombinant Mouse FGF2 Protein
Recombinant Mouse FGF2 Protein
Recombinant Human FGF2 Protein, Plant
Recombinant Human FGF2 Protein, HEK
Recombinant Human FGF2 Protein
Recombinant Human FGF2 Protein
Recombinant Human FGF2 Protein
Recombinant Bovine FGF2 Protein
Bovine FGF2 Protein
Recombinant Human FGF2 Protein, sf9

FGF2 Antibodies:
FGF2 Polyclonal Antibody
FGF2 Polyclonal Antibody
FGF2 Monoclonal Antibody

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