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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal CD95 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
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Fax: 1-617-606-5019
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Or leave a message with a formal purchase
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Introduction
FAS / CD95 is a 36 kDa transmembrane type I receptor, which belongs to the NF/NGF receptor super-family. It is a potent inducer of apoptosis in cells of the immune system upon interaction with its natural ligand, CD95L. Although the CD95/CD95L system could play a role in tumor regression, tumor cells seem to down-regulate CD95 expression as a mechanism of resistance to CD95L-induced killing by T lymphocytes and NK cells. The Fas antigen is expressed on the surface of various cell types, including activated T and B lymphocytes and T lymphoblastoid cell line. CD95 is also expressed in a broad panel of non-transformed cells outside the immune system.
BP000322-CYT-125: Recombinant Human FAS
Source: E.coli-derived.
A single, non-glycosylated polypeptide chain containing 157 amino acids and having a molecular mass of 17.6 kDa.
The ED50 was determined by its ability to inhibit the cytotoxicity of Jurkat cells is between 10-15 ug/ml in the presence of 2 ug/ml of hFasL.
Purity> 95%, by SDS-PAGE and RP-HPLC.
Formulation: FAS protein was lyophilized from a 0.2 um filtered concentrated solution in 1x PBS, pH 7.4.
Reconstitution: It is recommended to reconstitute the lyophilized FAS in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other FAS Protein:
Recombinant Human FAS，His Tag
FAS Antibodies:
FAS Polyclonal Antibody
FAS Polyclonal Antibody
FAS Monoclonal Antibody
FAS Monoclonal Antibody
FAS (Ab-291) Polyclonal Antibody
FAS ELISA Kits:
Human FAS ELISA Kit
Mouse FAS ELISA Kit
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