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Conditions of optimal FAS antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Background
FAS (also known as surface antigen APO1 or CD95) is a member of the tumour-necrosis receptor factor family of death receptors, can induce apoptosis or, conversely, can deliver growth stimulatory signals. It acts as an inducer of both neurite growth in vitro and accelerated recovery after nerve injury in vivo. Fas antigen is expressed and functional on papillary thyroid cancer cells and this may have potential therapeutic significance. The FAS antigen shows structural homology with a number of cell surface receptors, including tumor necrosis factor (TNF) receptors and the low-affinity nerve growth factor receptor (NGFR) and is mapped to 10q24.1. And the FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signalling pathway has been shown to participate in immune escape and tumorigenesis.
PA000107-PA1119: FAS Polyclonal Antibody
Rabbit Polyclonal Antibody.
Specificity/Sensitivity: mouse, rat No cross reactivity with other proteins.
Applications: Western blot: At 1 ug/ml with the appropriate system to detect FAS in cells and tissues. Immunohistochemistry(P): At 1-2ug/ml to detect FAS in formalin fixed and paraffin embedded tissues. Immunohistochemistry(F): At 1-2ug/ml to detect FAS in formalin or acetone fixed tissues.
Reactivity: Mouse, Rat.
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of rat FAS, different from the related mouse sequence by seven amino acids.
Purification: Immunogen affinity purified.
Form of Antibody: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Isotype: Rabbit IgG.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Other FAS Antibodies:
FAS Polyclonal Antibody
FAS Monoclonal Antibody
FAS Monoclonal Antibody
FAS (Ab-291) Polyclonal Antibody
FAS Proteins:
Recombinant Human FAS，His Tag
Recombinant Human FAS
FAS ELISA Kits:
Mouse FAS ELISA Kit
Human FAS ELISA Kit
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