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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal FAK antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
FAK, (Focal Adhesion Kinase), also known as PTK2(protein tyrosine kinase 2), is a protein that, in humans, is encoded by the PTK2 gene. PTK2 is a focal adhesion-associated protein kinase involved in cellular adhesion (how cells stick to each other and their surroundings) and spreading processes (how cells move around). It has been shown that when FAK was blocked, breast cancer cells became less metastastic due to decreased mobility. This gene encodes a cytosolic protein tyrosine kinase that is found concentrated in the focal adhesions that form among cells attaching to extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases that included PYK2 but lacks significant sequence similarity to kinases from other subfamilies. With the exception of certain types of blood cells, most cells express FAK.
PA000343-PA1574: FAK Polyclonal Antibody
Rabbit Polyclonal Antibody.
Applications: WB 0.1-0.5 ug/ml.
Reactivity: Human, Rat, Mouse.
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human FAK, identical to the related rat and mouse sequences.
Form of Antibody: Lyophilized.
Reconstitution: 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Isotype: Rabbit IgG.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Other FAK Antibodies:
FAK Polyclonal Antibody
FAK (Ab-925) Polyclonal Antibody
FAK (Ab-910) Polyclonal Antibody
FAK (Ab-861) Polyclonal Antibody
FAK (Ab-843) Polyclonal Antibody
FAK (Ab-577) Polyclonal Antibody
FAK (Ab-576) Polyclonal Antibody
FAK (Ab-407) Polyclonal Antibody
FAK (Ab-397) Polyclonal Antibody
FAK (Ab-397) Polyclonal Antibody
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