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Conditions of optimal Erk2/p42 MAPK antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Background
Mitogen-activated protein kinase 1, also known as MAPK1, p42MAPK, and ERK2, is an enzyme which in humans is encoded by the MAPK1 gene.1 The gene is mapped to 22q11.2.2 And The protein encoded by this gene is a member of the MAP kinase family. The deduced 360-amino acid human ERK2 protein shares 98% identity with rat Erk2.3 The MAP kinase ERK2 is widely involved in eukaryotic signal transduction. Upon activation, it translocates to the nucleus of the stimulated cell, where it phosphorylates nuclear targets.4 Futhermore, the ERK pathway is necessary for experience-dependent plasticity and for long-term potentiation of synaptic transmission in the developing visual cortex.5 And the MAPK pathway is also involved in responses to NTN1.6
PA000533-C10500: p42 MAPK Polyclonal Antibody
Rabbit Polyclonal Antibody.
Specificity/Sensitivity: p42 MAPK antibody detects endogenous levels of total p42 MAPK protein.
Applications: WB: 1:500~1:1000 ELISA: 1:10000.
Reactivity: Human, Mouse, Rat.
Specificity/Sensitivity: p42 MAPK antibody detects endogenous levels of total p42 MAPK protein.
Applications: WB: 1:500~1:1000 ELISA: 1:10000.
Form of Antibody: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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