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Background Information:
Eprosartan belongs to angiotensin receptor blockers (ARBs) used in patients with high blood pressure and other conditions. It antagonizes the effect of angiotensin II (vasoconstriction and aldosterone secretion) by blocking the angiotensin II receptor (AT 1receptor) in vascular smooth muscle and the adrenal gland, producing decreased blood pressure (BP).
Reference:
1. Teitelbaum I, Chilvers M, Reiz RJ, The angiotensin receptor blocker eprosartan mesylate reduces pulse pressure in isolated systolic hypertension, Can J Cardiol. 2004 Oct; 20 Suppl C:11C-16C.
2. Conter HS, McKay DW, Reiz RJ, Eprosartan mesylate effectively reduces systolic and diastolic blood pressure in a Canadian primary care setting. Can J Cardiol. 2004 Oct;20 Suppl C:6C-10C.
APIM050348: EPROSARTAN MESYLATE
CAS No.: 144143-96-4.
Molecular Formula: C24H28N2O7S2.
Molecular Weight: 520.62.
Purity: >99% (HPLC).
QC: LC/MS, 1HNMR.
Solubility: Soluble in DMSO and water.
Storage: Store at 0-4°C (short term), -20°C (Long term), Desiccated.
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