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EPO-alpha Protein

Erythropoietin-alpha, Epoetin, EP, MGC138142

Catalog No. Product Name Size List Price (US$) Quantity
BP000180-CYT-325 Recombinant Human EPOA Fc-Chimera 10 ug 160.00
BP000180-CYT-325 Recombinant Human EPOA Fc-Chimera 1 mg 4800.00
Description

Introduction
This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.

BP000180-CYT-325: Recombinant Human EPOα Fc-Chimera

Source: Chinese Hamster Ovary Cells(CHO)-derived.
A dimeric, glycosilated, polypeptide chain consisting of two mature human EPO molecules linked to the Fc portion of human IgG1. The Fc component contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1.
The ED50 as determined by the dose-dependant stimulation of human megakaryoblastic leukemia cells is less than 2.0 ug/ml, corresponding to a Specific Activity of 0.5 MIU/mg.
Purity > 98%, by SDS-PAGE and RP-HPLC.
Formulation: Each mg of lyophilized powder contains 1x PBS pH-7.4.
Reconstitution: It is recommended to reconstitute the lyophilized Erythropoietin in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other EPO-alpha Proteins:
Recombinant Human EPOα, HEK
Recombinant Human EPOα

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