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Conditions of optimal EIF4E Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
EIF4E is part of the eukaryotic initiation factor 4 families, controls translation of maternal mRNAs in early embryos before the onset of zygotic transcription. EIF4E identifies and binds to the 7 methyl GTP cap structure of eukaryotic mRNAs, thus modulates the initiation of translation. EIF4E enables ribosome binding by inducing the unwinding of the mRNAs secondary structures.
BP001963-PRO-530: Recombinant Human Eukaryotic Translation Initiation Factor 4E (EIF4E) Protein
Source: E. coli-derived.
Recombinant Human EIF4E protein is a single, non-glycosylated polypeptide chain containing 237 amino acids (1-217 a.a.) and having a molecular weight of 27.2 kDa. Recombinant Human EIF4E protein is fused to a 20 aa His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Purity: > 85.0% as determined by SDS-PAGE.
Formulation: The EIF4E 0.5 mg/ml protein solution contains 20 mM Tris-HCl, pH-8, and 10% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
eIF4E Antibodies:
eIF4E (Ab-209) Polyclonal Antibody
eIF4E (Phospho-Ser209) Polyclonal Antibody
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