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EDG1 Antibody

HEXIM1; Sphingosine 1-phosphate receptor Edg-1; Sphingosine 1-phosphate receptor 1; S1P1; EDG1

Catalog No. Product Name Size List Price (US$) Quantity
PA001511-G082 EDG1 Polyclonal Antibody 50 ug 250.00
PA001511-G082 EDG1 Polyclonal Antibody 100 ug 350.00
Description

Introduction
S1PR1 (sphingosine-1-phosphate receptor 1) also known as S1P1 or EDG1 (endothelial differentiation gene 1) is a protein that in humans is encoded by the S1PR1 gene. S1P1 is a G-protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P). The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell?cell adhesion.

PA001511-G082: EDG1 Polyclonal Antibody

Rabbit Polyclonal Antibody.
Specificity/Sensitivity: EDG1 antibody detects endogenous levels of total EDG1 protein.
Applications: WB: 1:500~1:1000 IF: 1:500~1:1000 ELISA: 1:5000.
Reactivity: Human.
Immunogen: The antiserum was produced against synthesized peptide derived from internal of human EDG1.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form of Antibody: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

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