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DNA-PK Antibody

DNA- PKcs; DNA-dependent protein kinase catalytic subunit; DNPK1; P460; PRKD; PRKDC; XRCC7; kinase DNA-PK

Catalog No. Product Name Size List Price (US$) Quantity
PA001471-PA1970 DNA-PK Polyclonal Antibody 100 ug 350.00
Description

Background
PRKDC (Protein Kinase DNA-Activated Catalytic Subunit), also called DNAPK, HYRC1, p350 or DNPK1, is an enzyme that in humans is encoded by the PRKDC gene. DNA-PKcs belongs to the phosphatidylinositol 3-kinase-related kinase protein family. Satoh et al. (1997) mapped the MCM4 gene to 8q11.2 by FISH. Based on the close proximity of the PRKDC and MCM4 genes, it was assumed that the PRKDC gene also maps to this location. Anderson and Lees-Miller (1992) noted that DNA-PK had been shown in vitro to phosphorylate several transcription factors, suggesting that it functions in cell homeostasis by modulating transcription. Daniel et al. (1999) demonstrated that the PRKDC protein participates in retroviral DNA integration, which is catalyzed by the viral protein integrase.

PA001471-PA1970: DNA-PK Polyclonal Antibody

Rabbit Polyclonal Antibody.
Applications: WB 0.1-0.5 ug/ml.
Reactivity: Human.
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human PRKDC.
Purification: Immunogen affinity purified.
Form of Antibody: Lyophilized. Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Isotype: Rabbit IgG.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.


Other DNA-PK Antibodies:
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DNA-PK (Ab-2647) Polyclonal Antibody
DNA-PK (Ab-2638) Polyclonal Antibody
DNA-PK (Ab-2612) Polyclonal Antibody
DNA-PK (Ab-2609) Polyclonal Antibody
DNA-PK (Ab-2056) Polyclonal Antibody

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