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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal Cytokeratin Peptide 18 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
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Or leave a message with a formal purchase
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Background
Intermediate filaments (IFs) are a structurally related family of cellular proteins that appear to be intimately involved with the cytoskeleton. Human keratin 18(KRT18) and the homologous mouse Endo B are type I IF protein subunits whose expression is restricted in adults to a variety of simple epithelial tissues. The KRT18 gene is 3,791 bp long and the keratin 18 protein is coded for by 7 exons. The K18 gene is 3791 bp in length and the K18 protein is coded for by seven exons. By Southern blotting using the genomic DNA PCR product, the gene for keratin 18 is assigned to chromosome 12. Mutation of human keratin 18 in association with cryptogenic cirrhosis
PA000028-MA1026: Cytokeratin Peptide 18 Monoclonal Antibody
Mouse Monoclonal Antibody.
Specificity/Sensitivity: Human, rat. No cross reactivity with other proteins.
Applications: Western blot: At 0.5-1 ug/ml with the appropriate system to detect cytokeratin peptide 18 in cells and tissues. Immunohistochemistry(P): At 1-2?g/ml to detect cytokeratin peptide 18 in formalin fixed and paraffin embedded tissues. Immunohistochemistry(F): At 0.5-2 ug/ml to detect cytokeratin peptide 18 in formalin or acetone fixed tissues.
Reactivity: Human, Rat.
Immunogen: The human epidermal carcinoma A-431 and MCF-7 human breast cancer cell lines.
Purification: Purified by the goat anti-mouse IgG affinity chromatography.
Form of Antibody: Lyophilized from 1.2% sodium acetate, with 2 mg BSA and 0.01 mg NaN3 as preservative.
Clone: CK-18.
Isotype: Mouse IgG1.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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