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Home > Antibodies > A-Z Primary Antibodies > Cytoglobin Antibody

Cytoglobin Antibody

CYGB, HGB, STAP

Catalog No. Product Name Size List Price (US$) Quantity
PA006520-PA1657 Cytoglobin Polyclonal Antibody 100 ug 350.00
Description

Background
Cytoglobin(CYGB),also called HGB or STAP, is a ubiquitously expressed hexacoordinate hemoglobin that may facilitate diffusion of oxygen through tissues, scavenge nitric oxide or other reactive oxygen species, or serve a protective function during oxidative stress. The cytoglobin gene is mapped on 17q25.1. The CYGB gene contains 4 exons and spans about 9 kb. Cytoglobin has many elements common to vertebrate globins, including invariant histidine residues, and the amino acids that form the heme pocket share similarity with pentacoordinate myoglobin. In contrast to the high oxygen affinities displayed by most hexacoordinate hemoglobins, the characteristics of CYGB indicate that it can facilitate oxygen transport. Because the oxygen affinity of CYGB is more similar to myoglobin than to neuroglobin, and the oxy form of CYGB resists autooxidation, CYGB is proposed to represent a tissue oxygen reservoir by Sawai et al.

PA006520-PA1657: Cytoglobin Polyclonal Antibody

Rabbit Cytoglobin Antibody.
Application: WB: 0.1-0.5 ug/ml.
Reactivity: Human, Rat.
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human Cytoglobin, identical to the related rat sequence, different from the related mouse sequence by one amino acid.
Purification: Immunogen affinity purified.
Form of Atibody: Lyophilized.

Storage/Stability: Stable for 1 year at -20°C and 1 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

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