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CYB5R3 Antibody

NADH-cytochrome b5 reductase 3,EC 1.6.2.2; Cytochrome b5 reductase; B5R; Diaphorase-1

Catalog No. Product Name Size List Price (US$) Quantity
PA001360-R12-2664 CYB5R3 Polyclonal Antibody 50 ug 250.00
PA001360-R12-2664 CYB5R3 Polyclonal Antibody 100 ug 350.00
Description

Introduction
NADH-cytochrome b5 reductase 3 is an enzyme that in humans is encoded by the CYB5R3 gene. Two forms of NADH-cytochrome b5 reductase are known, a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The former exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains. The soluble form has only the catalytic domain. This gene encodes both forms of the enzyme which arise from tissue-specific alternative transcripts that differ in the first exon. Mutations in this gene cause methemoglobinemias.

PA001360-R12-2664: CYB5R3 Polyclonal Antibody

Rabbit Polyclonal Antibody.
Specificity/Sensitivity: CYB5R3 antibody detects endogenous levels of CYB5R3.
Applications: WB: 1:500~1:1000; IHC: 1:50~1:100; ELISA: 1:10000.
Reactivity: Human, Mouse, Rat.
Immunogen: The antiserum was produced against synthesized peptide derived from human CYB5R3.
Purification: The antibody was affinity-purified from rabbit anti-serum by immunogenic peptide affinity-chromatography.
Form of Antibody: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

Other CYB5R3 Antibody:
CYB5R3 Polyclonal Antibody

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