Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
|---|
Conditions of optimal CYB5R1 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
NADH-cytochrome b5 reductase 1 (CYB5R1) belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. This reductase contains 1 FAD-binding FR-type domain and is involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction. Cytochrome b5 reductase, a flavoprotein that has an NADH binding site, can provide electrons to p450 monooxygenases through cytochrome b5. Reactions catalyzed by P450 show that the properties of the associated electron transport proteins that support P450-1 activity in mutants are consistent with cytochroe b5: NADH-cytochrome b5 oxidoreductase (cyt b5: cyt b5 reductase). Experiments have indicated that a flavoprotein is involved in the reaction that GA12 synthesis from GA12-aldehyde and consistent with participation of cytochrome b5 reductase which has an FAD prosthetic group. Added cytochrome b5 would enhance coupling of cytochrome b5 reductase to the P450-1 monooxygenase facilitating electron transport, while added FAD would restore bound flavin that may have been lost from the cyt b5 reductase during microsome preparation.
PA001359-R12-2663: CYB5R1 Polyclonal Antibody
Rabbit Polyclonal Antibody.
Specificity/Sensitivity: CYB5R1 antibody detects endogenous levels of CYB5R1.
Applications: WB: 1:500~1:1000; ELISA: 1:10000.
Reactivity: Human, Mouse, Rat.
Immunogen: The antiserum was produced against synthesized peptide derived from human CYB5R1.
Purification: The antibody was affinity-purified from rabbit anti-serum by immunogenic peptide affinity-chromatography.
Form of Antibody: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Other CYB5R1 Antibody:
CYB5R1 Polyclonal Antibody
Copyright © 2009-2022 sydlabs.com. All rights reserved.
Use of this website means that you have read, understood, and accepted the Syd Labs Privacy Policy and Terms & Conditions.