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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal CXCR1 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
CXCR1 is one of two high-affinity receptors for the CXC chemokine interleukin-8 (IL-8), a major mediator of immune and inflammatory responses implicated in many disorders, including tumour growth1, 2, 3. IL-8, released in response to inflammatory stimuli, binds to the extracellular side of CXCR1. The ligand-activated intracellular signalling pathways result in neutrophil migration to the site of inflammation2. CXCR1 is a class A, rhodopsin-like G-protein-coupled receptor (GPCR), the largest class of integral membrane proteins responsible for cellular signal transduction and targeted as drug receptors4, 5, 6, 7. Despite its importance, the molecular mechanism of CXCR1 signal transduction is poorly understood owing to the limited structural information available.
PA003911-PA2080: CXCR1 Polyclonal Antibody
Rabbit Polyclonal Antibody.
Applications: WB 0.1-0.5 ug/ml IHC-P 0.5-1 ug/ml.
Reactivity: Human.
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human CXCR1.
Purification: Immunogen affinity purified.
Form of Antibody: Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
Isotype: Rabbit IgG.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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