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Conditions of optimal CST3 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
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Introduction
Cystatins are a superfamily of cysteine proteinase inhibitors found in both plants and animals. They comprise a group of proteinase inhibitors, widely distributed in tissues and body fluids, and form tight complexes with cysteine proteases such as cathepsin B, H, L and S. Cystatin C, a secreted molecule of this family, is of interest from biochemical, medicine and evolutionary points of view. Cystatin C, with molecular weight of 13260 Da, is composed of 120 amino acids, lacks carbohydrate and has two disulfide bridges located near the carboxyl terminus. Cystatin C is increased in patients with malignant diseases, and is related to the insufficiency of renal function and appears to be a better marker than creatinine. On the other hand, low levels of cystatin C involve cause the breakdown of the elastic laminae and, subsequently, the atherosclerosis and abdominal aortic aneurysm.
BP001929-PRO-597: Recombinant Mouse Cystatin-C (CST3) Protein
Source: E. coli-derived.
Recombinant Mouse Cystatin-C Protein is a single, non-glycosylated, polypeptide chain containing 134 amino acids and having a molecular mass of 15 kDa. The Mouse Cystatin-C is fused to His tag at N-Terminus. The Mouse Cystatin-C is purified by proprietary chromatographic techniques.
Purity: > 95% as determined by SDS-PAGE.
Formulation: The sterile filtered concentrated (0.5 mg/ml) protein solution was lyophilized with 20 mM Tris & 50 mM NaCl pH-7.5.
Reconstitution: Add 0.1 M Acetate buffer pH 4 to a working concentration of 0.5 mg/ml and let the lyophilized pellet dissolve completely.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other CST3 Proteins:
Recombinant Human Cystatin-C, Active Protein
Recombinant Canine Cystatin-C Protein
Human Cystatin-C Protein
Recombinant Human Cystatin-C Protein
Recombinant Rat Cystatin-C Protein
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