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CRNN Protein

Cornulin, 53 kDa Putative Calcium-Binding Protein, 53 kDa Squamous Epithelial-Induced Stress Protein, C1orf10, DRC1, PDRC1

Catalog No. Product Name Size List Price (US$) Quantity
BP001749-PRO-797 Recombinant Human CRNN Protein 25 ug 160.00
BP001749-PRO-797 Recombinant Human CRNN Protein 1 mg 2250.00
Description

Introduction
Cornulin is a member of the fused gene family of molecular chaperones. Human Cornulin contains N-terminus EF-hand domains and Ca2+ binding domains, and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. Cornulin involves in the mucosal/epithelial immune response and epidermal differentiation. Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When Cornulin is overexpressed in oral squamous carcinoma cell lines, it regulates negatively cell proliferation by the induction of G1 arrest.

BP001749-PRO-797: Recombinant Human Cornulin (CRNN) Protein

Source: E. coli-derived.
A single, non-glycosylated, polypeptide chain containing 515 amino acids (1-495 a.a.) and having a molecular mass of 55.7 kDa.
Purity: > 85% by SDS-PAGE.
Formulation: The CRNN solution contains 20 mM Tris-HCl pH-8 and 10% glycerol.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other CRNN Proteins:
Recombinant Human CRNN Protein

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