My Cart [ 0 ]
Home > Proteins & Peptides > A-Z Proteins  > CRNN Protein

CRNN Protein

Cornulin, 53 kDa Putative Calcium-Binding Protein, 53 kDa Squamous Epithelial-Induced Stress Protein, C1orf10, DRC1, PDRC1

Catalog No. Product Name Size List Price (US$) Quantity
BP001749-C117 Recombinant Human CRNN Protein 10 ug 126.00
BP001749-C117 Recombinant Human CRNN Protein 50 ug 378.00
BP001749-C117 Recombinant Human CRNN Protein 1 mg 2640.00
Description

Introduction
Cornulin is a member of the fused gene family of molecular chaperones. Human Cornulin contains N-terminus EF-hand domains and Ca2+ binding domains, and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. Cornulin involves in the mucosal/epithelial immune response and epidermal differentiation. Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When Cornulin is overexpressed in oral squamous carcinoma cell lines, it regulates negatively cell proliferation by the induction of G1 arrest.

BP001749-C117: Recombinant Human Cornulin (CRNN) Protein

Source: E. coli-derived.
Recombinant Human Cornulin (CRNN) Protein is expressed with sequence (Met1-Ser140) of Human Cornulin.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other CRNN Proteins:
Recombinant Human CRNN Protein

Related Links

See our Privacy Policy