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CRH Antibody

Corticotropin releasing hormone Antibody,CRF Antibody

Catalog No. Product Name Size List Price (US$) Quantity
PA000231-PA1128 CRH (CRF) Polyclonal Antibody 100 ug 350.00
Description

Background

CRH is a 41-amino acid peptide derived by enzymatic cleavage from a 191-amino acid preprohormone and is located on 8q13. It is made not only in the hypothalamus but also in peripheral tissues, such as T lymphocytes, and is expressed in very large amounts in the human placenta. As a placental clock, CRH controls the duration of pregnancy and that the timing of the rise in CRH may permit prediction of the onset of labor. Furthermore, CRH is the most proximal element of the HPA axis, and it acts as a central coordinator for neuroendocrine and behavioral responses to stress. In addition, placental secretion of CRH is a marker of the 'placental clock' that is active from an early stage in human pregnancy and determines the length of gestation and the timing of parturition and delivery.

PA000231-PA1128: CRH (CRF) Polyclonal Antibody

Rabbit Polyclonal Antibody.
Specificity/Sensitivity: Human, mouse, rat. No cross reactivity with other proteins.
Applications: WB 0.1-0.5 ug/ml IHC-P 0.5-1 ug/ml ICC 1 ug/ml IHC-F 0.5-1 ug/ml.
Reactivity: Human, Mouse, Rat.
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human CRH, identical to the related rat and mouse sequence.
Purification: Immunogen affinity purified.
Form of Antibody: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Isotype: Rabbit IgG.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

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