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Conditions of optimal Connexin 43 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Background
Connexins 43 (Cx43), also called GAP Junction Protein, alpha-1(GJA1). Connexin 43 is a member of the connexin gene family which abundantly expressed in the heart and liver and was mapped to 6q21-q23.2. Connexin43, the major protein of gap junctions in the heart, is targeted by several protein kinases that regulate myocardial cell-cell coupling. Mutations in the connexin43 gap-junction gene,which lead to abnormally regulated cell-cell communication, are associated with visceroatrial heterotaxia.
PA000164-PA1026: Connexin 43 Polyclonal Antibody
Rabbit Polyclonal Antibody.
Specificity/Sensitivity: Human, mouse, rat. No cross reactivity with other proteins.
Applications: Western blot: At 2 ug/ml with the appropriate system to detect Connexin 43 in cells and tissues. Immunohistochemistry(P): At 1-2 ug/ml to detect Connexin 43 in formalin fixed and paraffin embedded tissues.
Reactivity: Human, Mouse, Rat.
Immunogen: A peptide mapping at the C-terminus of human Connexin 43, identical to the related rat and mouse sequence.
Purification: Immunogen affinity purified.
Form of Antibody: Each vial contains 50% glycerol, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Isotype: Rabbit IgG.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Other Connexin 43 Antibodies:
Connexin 43 Polyclonal Antibody
Connexin 43 (Ab-367)Polyclonal Antibody
Connexin 43 (Ab-261) Polyclonal Antibody
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