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Collagen IV alpha 2 Antibody

CO4A2, Collagen alpha-2(IV) chain, alpha 2 type IV collagen, canstatin, collagen type IV alpha 2

Catalog No. Product Name Size List Price (US$) Quantity
PA001265-C12196 Collagen IV A2 Polyclonal Antibody 50 ug 250.00
PA001265-C12196 Collagen IV A2 Polyclonal Antibody 100 ug 350.00
Description

Introduction
Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins.

PA001265-C12196: Collagen IV α2 Polyclonal Antibody

Rabbit Polyclonal Antibody.
Specificity/Sensitivity: Collagen IV α2 antibody detects endogenous levels of total Collagen IV α2 protein.
Applications: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:500~1:1000 ELISA: 1:20000.
Reactivity: Human, Mouse.
Immunogen: The antiserum was produced against synthesized peptide derived from internal of human Collagen IV α2.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form of Antibody: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

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