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Conditions of optimal CNTF Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
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Fax: 1-617-606-5019
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Or leave a message with a formal purchase
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Introduction
Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83% homology in their protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle cytokines share gp130 as a signal transducing subunit in their receptor complexes. CNTF, like FGF acidic, FGF basic, and PD-ECGF (platelet-derived.endothelial cell growth factor), does not possess a signal sequence that would allow secretion of the factor by classical secretion pathways.
BP001011-CYT-573: Recombinant Human CNTF Ciliary Neurotrophic Factor (CNTF) Protein, His Tag
Source: E. Coli-derived.
Predicted molecular mass: 25 kDa.
Purity: > 95% by SDS-PAGE and RP-HPLC.
Formulation: CNTF His tag protein solution contains 20 mM Tris buffer pH-8 and 1 mM DTT.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other CNTF Proteins:
Recombinant Rat CNTF Protein
Recombinant Mouse CNTF Protein
Recombinant Human CNTF Protein
Recombinant Human CNTF Protein
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