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CK19 Antibody

cytoskeletal 19

Catalog No. Product Name Size List Price (US$) Quantity
PA005149-PA1335 ck19 Polyclonal Antibody 100 ug 350.00
Description

Background
Keratin, type I cytoskeletal 19 is a protein that in humans is encoded by the KRT19 gene.[1][2]The protein encoded by this gene is a member of the keratin family.It is specifically expressed in the periderm, the transiently superficial layer that envelops the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.[2]Due to its high sensitivity, KRT19 is the most used marker for the RT-PCR-mediated detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients.Keratin 19 is often used together with keratin 8 and keratin 18 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood [3].

PA005149-PA1335: CK19 Polyclonal Antibody

Rabbit Polyclonal Antibody.
Specificity/Sensitivity: Human, No cross reactivity with other proteins.
Applications: WB 0.5 ug/ml, IHC-P 0.5 ug/ml, ICC 0.5 ug/ml.
Reactivity: Human.
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human CK19 (379-392 aa), identical to the related mouse and rat sequence.
Purification: Immunogen affinity purified.
Form of Antibody: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Isotype: Rabbit IgG.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

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