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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal CDCA8 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
CDCA8 is a component of the chromosomal passenger complex (CPC). The CPC complex has crucial functions at the centromere in ensuring accurate chromosome placement and isolation and is obligatory for chromatin-induced microtubule stabilization and spindle assembly. In the complex, CDCA8 protein is needed to direct the CPC to centromeric DNA. Removal of CDCA8 delays mitotic progression and causes kinetochore-spindle to mis-attach.
BP001875-PRO-222: Recombinant Human Cell Division Cycle Associated 8 (CDCA8) Protein
Source: E. coli-derived.
Recombinant Human CDCA8 fused with a 21 amino acid His tag at N-terminus is a single, non-glycosylated, polypeptide chain containing 283 amino acids (19-280a.a.) and having a molecular mass of 31.6 kDa. The CDCA8 is purified by proprietary chromatographic techniques.
Purity: > 90.0% as determined by SDS-PAGE.
Formulation: The CDCA8 solution (0.25 mg/1 ml) contains 20 mM Tris-HCl buffer (pH 8.0), 50% glycerol, 1 mM DTT, 1 mM EDTA and 0.2 M NaCl.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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