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Conditions of optimal CDC25A Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
M-phase inducer phosphatase 1 (CDC25A) belongs to the CDC25 family of phosphatases. CDC25A is essential for progression from G1 to the S phase of the cell cycle. CDC25A activates the cyclin-dependent kinase CDC2 by eliminating 2 phosphate groups. CDC25A is specifically degraded in reaction to DNA damage, which inhibits cells with chromosomal abnormalities from progressing in the course of cell division. CDC25A is an oncogene, though its exact function in oncogenesis has not been determined.
BP001870-ENZ-091: Recombinant Human Cell Division Cycle 25A (CDC25A) Protein
Source: E. coli-derived.
Recombinant Human CDC25A fused with a 36 amino acid His tag at N-terminus is a single, non-glycosylated, polypeptide chain containing 560 amino acids (1-524 a.a.) and having a molecular mass of 63.2 kDa. The CDC25A is purified by proprietary chromatographic techniques.
Purity: > 80.0% as determined by SDS-PAGE.
Formulation: The CDC25A solution (0.25 mg/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 5 mM DTT, 20% glycerol, 0.2 M NaCl and 1 mM EDTA.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
CDC25A Antibodies:
CDC25A Polyclonal Antibody
CDC25A Polyclonal Antibody
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