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CDC25A Antibody

CDC25M3; Dual specificity phosphatase Cdc25A; M-phase inducer

Catalog No. Product Name Size List Price (US$) Quantity
PA000389-PA1545 CDC25A Polyclonal Antibody 100 ug 350.00
Description

Background

The human CDC25 tyrosine phosphatases trigger activation of CDC2 by removing inhibitory phosphate from tyrosine and threonine residues of the cyclin-dependent kinases.The genes encoding these phosphatases are suspected of being potential oncogenes because of their role in promoting cell division. Three human CDC25 genes have been identified: CDC25A, CDC25B , and CDC25C . The CDC25A gene is mapped to 3p21 .in rodent cells, human CDC25A or CDC25B but not CDC25C phosphatases cooperate with either the gly12-to-val mutation of the HRAS gene or loss of RB1 in oncogenic focus formation.

PA000389-PA1545: CDC25A Polyclonal Antibody

Rabbit Polyclonal Antibody.
Applications: WB 0.1-0.5 ug/ml; IHC-P 0.5-1 ug/ml.
Reactivity: Human, Rat, Mouse.
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human CDC25A, identical to the related rat and mouse sequence.
Purification: Immunogen affinity purified.
Form of Antibody: Lyophilized.
Reconstitution: 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Isotype: Rabbit IgG.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

Other CDC25A Antibody:
CDC25A Polyclonal Antibody

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