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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal CD44 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Background
The CD44 gene, which is a transmembrane protein, is expressed as a family of molecular isoforms generated from alternative RNA splicing and posttranslational modifications. The gene, which contains 19 exons spanning some 50 kb of genomic DNA, is a widely expressed integral membrane protein that acts as a receptor for hyaluronan (HA) and is important to cell-extracellular matrix interaction. CD44 binding with HA can play an important role in cellular aggregation and tumor cell growth. CD44 is necessary for limb development and functions in a novel growth factor presentation mechanism. A specific CD44 splice variant is crucial for the proliferation of these mesenchymal cells. CD44 glycoproteins are involved in leukocyte extravasation but also in the regulation of growth factor activation, stability, and signaling. Moreover, it plays a pivotal role in arteriogenesis.
PA000167-B0847: CD44 (Ab-706) Polyclonal Antibody
Rabbit Polyclonal Antibody.
Specificity/Sensitivity: CD44 (Ab-706) antibody detects endogenous levels of total CD44 protein.
Applications: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000.
Reactivity: Human, Mouse, Rat.
Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human CD44 around the phosphorylation site of serine 706 (S-K-SP-Q-E).
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form of Antibody: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Other CD44 Antibodys:
FITC Conjugated CD44 Monoclonal Antibody
FITC Conjugated CD44 Monoclonal Antibody
CD44 Monoclonal Antibody
CD44 Monoclonal Antibody
CD44 Monoclonal Antibody
Biotin Conjugated CD44 Monoclonal Antibody
Biotin Conjugated CD44 Monoclonal Antibody
CD44 Protein:
Recombinant Human CD44 Protein
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