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CD4 Antibody

CD4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4 precursor

Catalog No. Product Name Size List Price (US$) Quantity
PA001078-ANT-145 CD4 Monoclonal Antibody 500 ug 160.00
PA001078-ANT-145 CD4 Monoclonal Antibody 1 mg 290.00
Description

Background
CD stands for 'cluster of differentiation'; the number that follows is arbitrarily assigned. In the full designation the cell type and nature and molecular weight of the antigen are given in brackets; for CD4,this is as follows: [T,gp55] .CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.

PA001078-ANT-145: CD4 Monoclonal Antibody

Mouse Monoclonal Antibody.
Applications: Blocking and staining antibody. Blocks blinding of HIV to CD4. For staining, use 10 ul/106 cells. Titer for blocking T cell activation should be determined by the investigator.
Reactivity: Human.
Immunogen: Purified human PBL CD4+ T cells.
Purification: Ion exchange column.
Form of Antibody: 1 ug/ml in PBS (after reconstitution).
Clone: hCD4.
Isotype: Mouse IgG2b.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

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