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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal CD3 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Background
The alpha-beta heterodimeric T-cell antigen receptor binds antigen in association with major histocompatibility complex proteins on host cell surfaces. These 2 disulfide-linked glycoproteins, TCRA and TCRB are associated on T-cell surfaces with a complex of proteins called CD3 (formerly T3).Human CD3 consists of at least 4 proteins: gamma, delta , epsilon, and zeta . The CD3-gamma/CD3-delta gene pair is within 300 kb of the CD3-epsilon gene and therefore these genes form a tightly linked cluster on 11q23. The clustering may be significant in terms of their simultaneous activations during T-cell development.
PA000021-ANT-137: CD3 (epsilon chain) Monoclonal Antibody
Mouse Monoclonal Antibody.
Applications: Blocking, staining and activating antibody. For staining, use 10 ul/106 cells. Titer for blocking and activating T cells should be determined by the investigator.
Reactivity: Human.
Immunogen: Purified human PBL T cells.
Purification: Ion exchange column.
Form of Antibody: 1 ug/ml in PBS (after reconstitution).
Clone: hCD3.
Isotype: Mouse IgG2a.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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