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CD22 Antibody

Catalog No. Product Name Size List Price (US$) Quantity
PA006038-PA1018 CD22 Polyclonal Antibody 100 ug 350.00
Description

Background

CD22 is a surface glycoprotein of B lymphocytes that is rapidly phosphorylated on cytoplasmic tyrosines after antigen receptor cross-linking. CD22 is a negative regulator of antigen receptor signaling whose onset of expression at the mature B cell stage may serve to raise the antigen concentration threshold required for B cell triggering. The human CD22 gene is expressed specifically in B lymphocytes and likely has an important function in cell-cell interactions. The B cell coreceptor CD22 plays an important role in regulating signal transduction via the B cell Ag receptor.3 CD22 is located within the band region q13.1 of chromosome 19.

PA006038-PA1018: CD22 Polyclonal Antibody

Rabbit Polyclonal Antibody.
Specificity/Sensitivity: Human. No cross reactivity with other proteins.
Applications: Western blot: At 0.5-1 ug/ml with the appropriate system to detect CD22 in cells and tissues. Immunohistochemistry(P): At 0.5-1 ug/ml to detect CD22in formalin fixed and paraffin embeddedtissues.
Reactivity: Human.
Immunogen: A peptide mapping at the C-terminal end of human CD22, different from the relative sequence of mouse by three amino acids.
Purification: Immunogen affinity purified.
Form of Antibody: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Isotype: Rabbit IgG.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

Other CD22 Antibody:
CD22 Polyclonal Antibody

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