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CD160 Antibody

CD160 antigen , Natural killer cell receptor BY55, CD160, BY55

Catalog No. Product Name Size List Price (US$) Quantity
PA001062-C12076 CD160 Polyclonal Antibody 50 ug 250.00
PA001062-C12076 CD160 Polyclonal Antibody 100 ug 350.00
Description

Introduction
CD160 antigen is a protein that in humans is encoded by the CD160 gene.
CD160 is a 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.

PA001062-C12076: CD160 Polyclonal Antibody

Rabbit Polyclonal Antibody.
Specificity/Sensitivity: CD160 antibody detects endogenous levels of total CD160 protein.
Applications: WB: 1:500~1:1000 ELISA: 1:20000.
Reactivity: Human.
Immunogen: The antiserum was produced against synthesized peptide derived from internal of human CD160.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form of Antibody: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

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