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Conditions of optimal CCRL2 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
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Or leave a message with a formal purchase
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Introduction
C-C chemokine receptor-like 2 is a protein that in humans is encoded by the CCRL2 gene. Recently it was found that CCRL2 also acts as a receptor for the chemokine chemerin. This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.
PA001055-G061: CCRL2 Polyclonal Antibody
Rabbit Polyclonal Antibody.
Specificity/Sensitivity: CCRL2 antibody detects endogenous levels of total CCRL2 protein.
Applications: WB: 1:500~1:1000 IF: 1:500~1:1000 ELISA: 1:20000.
Reactivity: Human.
Immunogen: The antiserum was produced against synthesized peptide derived from internal of human CCRL2.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form of Antibody: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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