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CCL1-Fc (Mouse) Protein

C-C Motif Chemokine 1, Small-Inducible Cytokine A1, T Lymphocyte-Secreted Protein I-309, SCYA1
Catalog No. Product Name Size List Price (US$) Quantity
BP000040-0011 Recombinant Mouse CCL1 Protein 25 ug 250.00

Chemokine (C-C Motif) Ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells, which play a central role during immunoregulatory and inflammaion processes. Human CCL1 has been assumed to be a homologue of the mouse TCA3. While the two proteins share only approximately 42% amino acid sequence identity, both chemokines contain an extra pair of cysteine residues not found in most other chemokines. CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with cell surface chemokine receptor CCR8. CCL1 is identified as a potent inhibitor of HIV-1 envelope-mediated cell-cell fusion and virus infection.

BP000040-0011: Recombinant Mouse C-C Motif Chemokine 1 (CCL1) Protein

Source: CHO cell cell-derived.
A DNA sequence encoding the secreted form of mouse CCL1 isoform 1 (P10146-1) (Lys 24-Cys 92) was fused with the Fc region of human IgG1 at the N-terminus.
Predicted molecular mass: 36.2 kDa.
Purity: >92% determined by SDS-PAGE.
Endotoxin: < 1.0 EU per ug of the protein as determined by the LAL method.
Fusion protein: Human Fc fused to the C-terminus of mouse CCL1.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20°C to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20°C to -70°C under sterile conditions after reconstitution.

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