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CA14 Antibody

Carbonic anhydrase 14; EC 4.2.1.1; Carbonic anhydrase XIV; Carbonate dehydratase XIV; CA-XIV

Catalog No. Product Name Size List Price (US$) Quantity
PA000968-C14937 CA14 Polyclonal Antibody 50 ug 250.00
PA000968-C14937 CA14 Polyclonal Antibody 100 ug 350.00
Description

Introduction
Carbonic anhydrase 14 is an enzyme that in humans is encoded by the CA14 gene.
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XIV is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles. In melanocytic cells CA14 gene expression may be regulated by MITF.

PA000968-C14937: CA14 Polyclonal Antibody

Rabbit Polyclonal Antibody.
Specificity/Sensitivity: CA14 antibody detects endogenous levels of total CA14 protein.
Applications: WB: 1:500~1:1000 ELISA: 1:2000.
Reactivity: Human, Mouse, Rat.
Immunogen: The antiserum was produced against synthesized peptide derived from internal of human CA14.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form of Antibody: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

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